In 1984, Dutton made his Broadway debut in August Wilson's Ma Rainey's Black Bottom, winning a Theatre World Award and a Tony Award nomination for Best Actor. In 1988 Dutton played a killer in the television miniseries The Murder of Mary Phagan opposite Jack Lemmon and Kevin Spacey. 1990 brought him a second Best Actor Tony nomination for his role in another Wilson play, The Piano Lesson. Dutton also starred in Alien³, the debut film of director David Fincher then costarred in 1993's Rudy.
Dutton won Outstanding Guest Actor Emmy awards in 2002 and 2003 for his roles in The Practice and Without a Trace. In 1999, he starred in an ensemble cast in Aftershock: Earthquake in New York in which he played the Mayor of New York City. He co-starred with Tom Skerritt. Dutton gained acclaim for his show Roc shown on FOX television from 1991 to 1994, especially mid-run when the show was broadcast live. His work in this role won him an NAACP Image Award. He co-starred in the popular but short-lived 2005 CBS science fiction series, Threshold.
In 2000, Dutton directed the critically acclaimed HBO mini series The Corner. The miniseries was close to his heart for Dutton grew up on the streets of East Baltimore. It was adapted from The Corner: A Year in the Life of an Inner-City Neighborhood (Broadway Books, 1997) by David Simon (a reporter for the Baltimore Sun) and Ed Burns (a retired Baltimore homicide detective). The Corner won several Emmys in 2000, including that for best miniseries. Dutton won for his direction of the miniseries.
He starred as Montgomery County, Maryland Police Chief Charles Moose in the 2003 made-for-TV movie D.C. Sniper: 23 Days of Fear, and appears in Season 2 of The L Word. Dutton also appeared in an episode of The Sopranos. He most recently guest starred on House as the father of Doctor Eric Foreman (Omar Epps) and on Sleeper Cell: American Terror as the father of undercover FBI agent Darwyn Al-Sayeed. He also directed two episodes of Sleeper Cell.
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